news

New Publication on Cellodextrin Production

The CARBAFIN team is proud to present another peer-reviewed publication about improved cellodextrin production processes! Cellodextrins are oligosaccharides that have promising applications as nutrial ingredients as long as they are soluble enough. The solubility mainly depends on the degree of polymerization, which is an important parameter for the biotechnological production.

The recent publication proposes a cascade approach by using three enzymes (glycoside phosphorylase cascade) for the conversion of sucrose and glucose into short-chain (soluble) cellodextrins. Our CARBAFIN team identified the three major factors that are crucial for an efficient reaction: the ratio of enzyme activity, the ratio of sucrose and glucose (substrate) and the phosphate concentration used. The article describes a balanced approach for product solubility control and yield and gives some important hints about upstream and downstream processing.

Preview to the Biotechnology Journal at Wiley Online Library

For reading the full article, please follow the link. The article was published in the Biotechnology Journal (Nov. 2019).

 

CARBAFIN @esib 2019

From 18th to 20th November the CARBAFIN took the great opportunity to exhibit its concept at the H2020 corner of the European Summit of Industrial Biotechnology (esib 2019, www.esib.at). About 500 attendees from all over the world discussed about “bioproduction in the sense of bioeconomy” and took the chance for chat with our project staff at the exhibition table. Additionally, CARBAFIN presented its technologies and ideas in the frame of a science flash.

One day after the event, the consortium directly went into its 4th project progress meeting and welcomed the external advisory board for an inspiring stakeholder workshop.

CARBAFIN presented at EUROCARB XX

Our team member Chao Zhong presented his results at the EUROCARB XX, taking place in Leiden, Netherlands from 30th June to 4th July 2019.

He showed his process of a controlled polymerization of cellodextrins from glucose by using coupled cellobiose and cellodextrin phosphorylase. The resulting soluble cellodextrins have interesting applications as ingredients for human and animal nutrition. The study provides the basis for an efficient and product DP-(degree of polymerization)-controlled biocatalytic synthesis of cellodextrins from expedient substrates.

You are interested in the full presentation? Please contact us.

First Paper released

18 months are over and the first CARBAFIN review meeting took place in Ghent, Belgium. A lot of work has been done, and there is still a lot to do! The first CARBAFIN publication was published recently and is about the enzymatic production of cellodextrins with the help of a novel cellobiose phosphorylase from Clostridium cellulosi.

Get the full article here.

You are interested in corresponding data? Please follow the link to Zenodo database.

 

Poster presentation at RRB15

CARBAFIN people are eager to promote the central project idea at numerous international conferences and fairs! After visiting In-cosmetics 2018, RRB-14 or Biomarkets 2019, project members from University of Ghent represented CARBAFIN with a poster at the International Conference on Renewable Resources & Biorefineries (RRB-15) in Toulouse, France.

You missed the chance to meet us there? Take a look at our poster and get an idea about our objectives. And meet us at the upcoming events, where CARBAFIN is participating:

CARBAFIN in networking action

On 7th May 2019, the Human Technology Styria Cluster (HTS) visited acib GmbH in the frame of its “Fast Forward 4U” event line. About 50 Austrian representatives from industry and academia were welcomed in Graz for networking and gained insights into actual topics of industrial biotechnology in the labs of acib and TU Graz.

CARBAFIN was a topic in Christiane Luley’s presentation, dealing with the generation of new value chains by biotechnology. After a short lab tour, guests came together at the networking buffet and enjoyed the rest of an inspiring evening.